Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956303 | 0.88 | DNM1 (0.61) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8956620 | 0.88 | DNM1 (0.56) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8411348 | 0.86 | DNM1 (0.64) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20834977 | 0.84 | DNM1 (0.44) | DNM1ACKR3TERT | |
| SCHEMBL8422571 | 0.84 | DNM1 (0.67) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8411584 | 0.84 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8956676 | 0.84 | DNM1 (0.57) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24412648 | 0.83 | DNM1 (0.65) | DNM1ALDH1A1CASP2 | |
| SCHEMBL4577306 | 0.83 | DNM1 (0.55) | DNM1ALDH1A1 | |
| SCHEMBL7140311 | 0.83 | DNM1 (0.61) | DNM1ACKR3ALDH1A1TERTCASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |