Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956669 | 0.82 | MEN1 (0.39) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8956996 | 0.81 | MEN1 (0.38) | MEN1KMT2AALDH1A1POLBMCL1 | |
| SCHEMBL24453194 | 0.79 | MEN1 (0.38) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL8956580 | 0.78 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2MCL1 | |
| SCHEMBL16202803 | 0.77 | MEN1 (0.36) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL8956512 | 0.75 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8957040 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EEPHX2 | |
| SCHEMBL5932298 | 0.75 | — | — | |
| SCHEMBL8957018 | 0.75 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL22856326 | 0.74 | MEN1 (0.50) | MEN1KMT2AEPHX2SMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |