Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.68 |
| ▸ | FNTA | P49354 | 7/20 | 0.53 |
| ▸ | FNTB | P49356 | 7/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957083 | 1.00 | TACR1 (0.68) | TACR1FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL8956845 | 1.00 | TACR1 (0.68) | TACR1FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL8956812 | 0.94 | TACR1 (0.64) | TACR1FNTAFNTBKMT2AMEN1 | |
| SCHEMBL9247977 | 0.94 | TACR1 (0.64) | TACR1FNTAFNTBKMT2AMEN1 | |
| SCHEMBL8956834 | 0.92 | TACR1 (0.61) | TACR1FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL9245221 | 0.92 | TACR1 (0.61) | TACR1FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL8545840 | 0.91 | TACR1 (0.67) | TACR1FNTAFNTBKMT2AMEN1 | |
| SCHEMBL8956909 | 0.91 | TACR1 (0.67) | TACR1FNTAFNTBKMT2AMEN1 | |
| SCHEMBL8956821 | 0.90 | TACR1 (0.61) | TACR1FNTAFNTBOPRD1OPRK1 | |
| SCHEMBL8956765 | 0.90 | TACR1 (0.61) | TACR1FNTAFNTBOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484804-A | Perhydroisoindole derivatives as antagonists of substance P | RHONE-POULENC RORER S.A. (FR) | 1996-01-16 | — | — | US | disclosed |