Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956834 | 1.00 | TACR1 (0.61) | TACR1OPRK1OPRD1FNTAFNTB | |
| SCHEMBL8956845 | 0.92 | TACR1 (0.68) | TACR1OPRK1OPRD1FNTAFNTB | |
| SCHEMBL8957083 | 0.92 | TACR1 (0.68) | TACR1OPRK1OPRD1FNTAFNTB | |
| SCHEMBL8957044 | 0.92 | TACR1 (0.68) | TACR1OPRK1OPRD1FNTAFNTB | |
| SCHEMBL9247977 | 0.90 | TACR1 (0.64) | TACR1FNTAFNTBSIGMAR1ALDH1A1 | |
| SCHEMBL8956812 | 0.90 | TACR1 (0.64) | TACR1FNTAFNTBSIGMAR1ALDH1A1 | |
| SCHEMBL8956909 | 0.85 | TACR1 (0.67) | TACR1FNTAFNTBSIGMAR1ALDH1A1 | |
| SCHEMBL8545840 | 0.85 | TACR1 (0.67) | TACR1FNTAFNTBSIGMAR1ALDH1A1 | |
| SCHEMBL8956765 | 0.84 | TACR1 (0.61) | TACR1OPRK1OPRD1FNTAFNTB | |
| SCHEMBL8956821 | 0.84 | TACR1 (0.61) | TACR1OPRK1OPRD1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463077-A | Exhibit substance P antagonist activity | RHONE-POULENC RORER S.A. (FR) | 1995-10-31 | — | — | US | disclosed |