Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.91 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.91 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.91 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14129889 | 0.95 | CYP2D6 (1.00) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL31140249 | 0.89 | CYP2D6 (0.88) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9082298 | 0.85 | CYP2D6 (0.66) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28202352 | 0.82 | CYP2D6 (0.76) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9777426 | 0.80 | CYP2D6 (0.63) | CYP2D6CYP19A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27375070 | 0.80 | CYP2D6 (0.91) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL12658868 | 0.80 | CYP2D6 (0.91) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9618529 | 0.80 | KDM4E (0.74) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9450010 | 0.80 | KDM4E (0.74) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9074735 | 0.80 | KDM4E (0.74) | CYP2D6CYP19A1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5562859-A | SWITCHING AND DISPLAY DEVICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-08 | — | — | US | disclosed |