Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074735 | 1.00 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9618529 | 1.00 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL13402231 | 0.97 | KDM4E (0.69) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL13402174 | 0.92 | KDM4E (0.64) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9229557 | 0.92 | CASP3 (0.68) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL2448227 | 0.92 | KDM4E (0.72) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9814407 | 0.91 | L3MBTL1 (0.63) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8719480 | 0.91 | NR5A1 (0.66) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10554835 | 0.90 | RAB9A (0.68) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL10560528 | 0.90 | RAB9A (0.68) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |