Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253155 | 0.87 | DRD2 (0.75) | DRD2MAPK1DRD3HTR1AADRA1D | |
| SCHEMBL30206503 | 0.86 | DRD2 (0.78) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL1255253 | 0.86 | DRD2 (0.78) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL4617829 | 0.85 | DRD2 (0.77) | DRD2MAPK1DRD3HTR1AADRA1D | |
| SCHEMBL10548333 | 0.84 | DRD2 (0.62) | DRD2MAPK1DRD3HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL11651993 | 0.84 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8980706 | 0.84 | DRD2 (0.76) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL9225440 | 0.84 | MAPK1 (0.81) | DRD2MAPK1DRD3ADRA1DADRA1A | |
| SCHEMBL12304200 | 0.84 | DRD2 (0.66) | DRD2MAPK1DRD3HTR1AADRA1D | |
| SCHEMBL5307095 | 0.83 | DRD2 (0.69) | DRD2MAPK1DRD3HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539107-A | REACTION OF CHLOROPYRIDINE AND CHLOROQUINOLINES WITH MERCAPTOANILINES OR BIS/O-AMINOPHENYL DISULFIDE | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |
| US-5446148-A | Chemical intermediates for making antitussive agent, antihistamines and antipsychotic agent; efficiency, by-product inhibition | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0611757-A1 | Process for the preparation of azaphenothiazines | ASTA Medica Aktiengesellschaft (DE) | 1994-08-24 | — | — | EP | disclosed |