SCHEMBL8957791

SCHEMBL8957791

CC(C)(C)C1=CC(Br)(C(C)(C)C)C=CC1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311841 0.76
SCHEMBL7200717 0.70
Butylated Hydroxytoluene SCHEMBL7247214 0.63 SMN1; SMN2 (0.49)
SCHEMBL4843472 0.57
SCHEMBL17495192 0.56
SCHEMBL3757024 0.53
SCHEMBL21777389 0.51
SCHEMBL27529973 0.50
SCHEMBL7111141 0.49
SCHEMBL18677072 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0557404-B1 ANTIVIRAL USE OF A 2,6-DI-t-BUTYLPHENOL COMPOUND SUBSTITUTED IN POSITION 4, PARTICULARLY IN RELATION TO HERPESVIRUSES AND PAPILLOMAVIRUSES FILECO SA (FR) 1996-05-15 EP disclosed
US-5487893-A Antiviral use of a 2,6-di-t-butylphenol compound substituted in 4 position against herpes viruses and papillomaviruses FILECO (FR) 1996-01-30 US disclosed
EP-0557404-A1 ANTIVIRAL USE OF A 2,6-DI-t-BUTYLPHENOL COMPOUND SUBSTITUTED IN POSITION 4, PARTICULARLY IN RELATION TO HERPESVIRUSES AND PAPILLOMAVIRUSES. FILECO SA (FR) 1993-09-01 EP disclosed
WO-1992008450-A2 ANTIVIRAL USE OF A 2,6-DI-t-BUTYLPHENOL COMPOUND SUBSTITUTED IN POSITION 4, PARTICULARLY IN RELATION TO HERPESVIRUSES AND PAPILLOMAVIRUSES FILECO (FR) 1992-05-29 WO disclosed