SCHEMBL8958346

SCHEMBL8958346

C=CC(=O)OOOC(=O)C(=C)[SiH3]

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.31
ALDH1A1 P00352 3/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26479 0.81 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3507426 0.78 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17984806 0.78 ALDH1A1 (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7871849 0.78 ALDH1A1 (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
Bromide SCHEMBL10699735 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL16555949 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7138892 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8958344 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL22319173 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
Hydrazine SCHEMBL9436989 0.76 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0589909-B1 A METHOD OF STRENGTHENING GLASS BRITISH TECH GROUP (GB) 1996-01-17 EP disclosed
US-5476692-A Method of strengthening glass BRITISH TECHNOLOGY GROUP LTD (GB) 1995-12-19 US disclosed
EP-0589909-A1 A METHOD OF STRENGTHENING GLASS. UNIV SHEFFIELD (GB) 1994-04-06 EP disclosed
WO-1992020633-A1 A METHOD OF STRENGTHENING GLASS THE UNIVERSITY OF SHEFFIELD (GB) 1992-11-26 WO disclosed