Ethylene Glycol

Ethylene Glycol

SCHEMBL8958377

NC(=O)NCCOCCNC(N)=O.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA4 P22748 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
ACHE P22303 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
EPHX2 P34913 1/20 0.31
MTNR1A P48039 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2523273 0.93 TSHR (0.46) CA2MEN1KMT2ASMN1; SMN2LMNA
Di(Hydroxyethyl)Ether SCHEMBL8958433 0.93 TSHR (0.46) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8958454 0.93 CA2 (0.50) CA2MEN1KMT2ASMN1; SMN2LMNA
Triethylene Glycol SCHEMBL8958148 0.91 MEN1 (0.48) CA2MEN1KMT2ASMN1; SMN2LMNA
Tetraethylene Glycol SCHEMBL8958300 0.91 MEN1 (0.48) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL6285604 0.91 MEN1 (0.48) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8958306 0.90 CA2 (0.53) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8958158 0.90 CA2 (0.53) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8958384 0.90 CA2 (0.53) CA2MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL8958443 0.90 CA2 (0.53) CA2MEN1KMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484457-A Continuous production of surface dyeings on cellulose fiber textile materials BASF AKTIENGESELLSCHAFT (DE) 1996-01-16 US disclosed
US-5224963-A Improving perspiration fastness BASF AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
US-5015754-A Cationic polyethers for fixing reative and direct dyes used for dyeing and printing cellulose textiles; washfastness BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed