Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95981 | 0.87 | TP53 (0.47) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL8958635 | 0.84 | TP53 (0.44) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL11317937 | 0.84 | TP53 (0.44) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| Hydrogen Sulfide SCHEMBL9001004 | 0.84 | TP53 (0.44) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| Acetic Acid SCHEMBL6932728 | 0.81 | FFAR3 (0.44) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL1641494 | 0.79 | — | — | |
| Acetic Acid SCHEMBL20593502 | 0.79 | FFAR3 (0.41) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL9715475 | 0.79 | — | — | |
| SCHEMBL16303293 | 0.77 | TP53 (0.38) | TP53ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL25385810 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117959425-A | Docetaxel prodrug and hematoporphyrin co-assembled nanoparticle as well as preparation method and application thereof | 山西医科大学 | 2024-05-03 | — | — | CN | claimed |
| CN-115300637-A | Chalcogen hybrid bond bridged dimer prodrug, self-assembled nanoparticles thereof, preparation method and application | 沈阳药科大学 | 2022-11-08 | — | — | CN | claimed |
| EP-1721932-B1 | Pneumatic tire with built-in sealant containing pre-hydrophobated silica | GOODYEAR TIRE & RUBBER (US) | 2008-08-13 | — | — | EP | claimed |
| US-20060254687-A1 | Pneumatic tire with built-in sealant containing pre-hydrophobated silica | SANDSTROM PAUL H | 2006-11-16 | — | — | US | claimed |
| EP-1721932-A1 | Pneumatic tire with built-in sealant containing pre-hydrophobated silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-11-15 | — | — | EP | claimed |
| US-6797757-B2 | RUBBER BLEND CONTAINING (TRI OR TETRA)SULFURDIPROPIONIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-09-28 | — | — | US | claimed |
| US-6660791-B2 | For recycling/wastes via grinding, compounding with carbon black, then vulcanizing with sulfur | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-12-09 | — | — | US | claimed |
| US-6653387-B2 | Composite of aluminum oxide hydroxide and tetrathiodipropionic acid and/or trithiodipropionic acid coupler | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-11-25 | — | — | US | claimed |
| US-20030060572-A1 | Alumina reinforced rubber composition which contains tetrathiodipropionic and/or trithiodipropionic acid coupling agent and article of manufacture, including a tire, having at least one component comprised of such rubber composition | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-03-27 | — | — | US | claimed |
| US-20030032685-A1 | Article, including tires, having component of rubber composition which contains particles of pre-vulcanized rubber and high purity trithiodipropionic acid | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-02-13 | — | — | US | claimed |
| EP-1277793-A2 | Article having a component of a rubbber composition which contains particles of prevulcanized rubber and a blend of tetrathiodipropionic and trithiodipropionic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-01-22 | — | — | EP | claimed |
| US-20030004243-A1 | Article, including tires, having component of rubber composition which contains particles of pre-vulcanized rubber and blend of tetrathiodipropionic and trithiodipropionic acids | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-01-02 | — | — | US | claimed |
| EP-1270661-A2 | Article having a component of a rubber composition which contains particles of pre-vulcanized rubber and high purity trithiodiproponic acid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-01-02 | — | — | EP | claimed |
| EP-0780429-A1 | Silica-filled rubber compositions containing a mixture of dithiodipropionic acid, trithiodipropionic acid and tetrethiodipropionic acid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-25 | — | — | EP | claimed |
| JP-9176381-A | — | — | None | — | — | JP | disclosed |
| JP-63265997-A | — | — | None | — | — | JP | disclosed |
| CN-118634194-A | Active targeting and response type double-drug-carrying synergistic nano drug-carrying micelle and application thereof | 贵州大学 | 2024-09-13 | — | — | CN | disclosed |
| EP-0780429-A1 | Silica-filled rubber compositions containing a mixture of dithiodipropionic acid, trithiodipropionic acid and tetrethiodipropionic acid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0780429-A1 | Silica-filled rubber compositions containing a mixture of dithiodipropionic acid, trithiodipropionic acid and tetrethiodipropionic acid | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| JP-S63265997-A | AQUEOUS LUBRICANT | IDEMITSU KOSAN CO LTD | 1988-11-02 | — | — | JP | disclosed |