Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471858 | 0.86 | KDM4E (0.60) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL7005379 | 0.85 | HRH3 (0.44) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL668560 | 0.85 | HRH3 (0.58) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL6249126 | 0.83 | HRH3 (0.57) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL8116743 | 0.82 | HRH3 (0.56) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL7009247 | 0.82 | HRH3 (0.56) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL3762622 | 0.81 | KDM4E (0.51) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL3611058 | 0.81 | HRH3 (0.61) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL8982278 | 0.81 | HRH3 (0.54) | HRH3CYP2D6HTTLMNAMAPT | |
| SCHEMBL3942245 | 0.79 | KDM4E (0.53) | HRH3CYP2D6HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |