Biphenyl

Biphenyl

SCHEMBL8958655

Cc1nc2cccccc-2n1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.58
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
RAB9A P51151 2/20 0.52
ALDH1A1 P00352 3/20 0.47
CCR1 P32246 1/20 0.46
CCR8 P51685 1/20 0.46
MAPT P10636 5/20 0.46
TP53 P04637 3/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 2/20 0.46
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ASIC3 Q9UHC3 1/20 0.43
KDM4E B2RXH2 2/20 0.42
PKM P14618 1/20 0.42
NOTUM Q6P988 1/20 0.42
GAA P10253 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16353106 0.83 KMT2A (0.60) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL17286932 0.83 KMT2A (0.60) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL10039374 0.82 KMT2A (0.60) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL12166282 0.81 KMT2A (0.50) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL12166272 0.80 KMT2A (0.49) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL12166264 0.78 KMT2A (0.51) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL12166284 0.78 KMT2A (0.47) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL18562524 0.78 KMT2A (0.55) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL19397307 0.78 KMT2A (0.70) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL14970094 0.77 TSHR (0.56) L3MBTL1KMT2AMEN1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8143552-A None JP disclosed
JP-H08143552-A CYCLOHEPTIMIDAZOLE DERIVATIVE, ITS PRODUCTION AND MEDICINE CONTAINING THE SAME KOTOBUKI SEIYAKU KK 1996-06-04 JP disclosed