SCHEMBL12166264

SCHEMBL12166264

Cc1nc(-c2ccccc2)cc(-c2cccc(-c3ccccc3)c2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.51
MAPT P10636 9/20 0.50
MEN1 O00255 9/20 0.50
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.50
HPGD P15428 4/20 0.50
TP53 P04637 4/20 0.50
KDM4E B2RXH2 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 2/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
ATM Q13315 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.49
RAB9A P51151 2/20 0.47
PKM P14618 1/20 0.47
MAOA P21397 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21030901 0.98 KMT2A (0.53) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL21031204 0.98 KMT2A (0.53) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL12166272 0.98 KMT2A (0.49) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL18562524 0.96 KMT2A (0.55) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL12166284 0.96 KMT2A (0.47) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL12166275 0.94 KMT2A (0.46) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL23615528 0.91 MAPT (0.54) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL16353106 0.90 KMT2A (0.60) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL17286932 0.90 KMT2A (0.60) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL10039374 0.89 KMT2A (0.60) KMT2AMAPTMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11659765-B2 Composition for organic optoelectronic element, organic optoelectronic element, and display device SAMSUNG SDI CO., LTD. (KR) 2023-05-23 US disclosed
US-11653564-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-05-16 US disclosed
US-11653564-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-05-16 US disclosed
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-07-22 US disclosed
EP-3483152-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-04-28 EP disclosed
US-10981880-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20170309831-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
WO-2017061810-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2017-04-13 WO disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
WO-2011060859-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 KMT2A 1221/4885MAPT 611/4885MEN1 3802/4885
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 KMT2A 2454/4885MAPT 428/4885MEN1 665/4885
US-10981880-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 KMT2A 2454/4885MAPT 428/4885MEN1 665/4885
US-11653564-B2 Compound and organic light-emitting device comprising same CRY1, CYP1A1, TMEM109 KMT2A 1084/4885MAPT 928/4885MEN1 289/4885
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 KMT2A 2454/4885MAPT 428/4885MEN1 665/4885
US-20170309831-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OR51E2 KMT2A 4687/4885MAPT 2526/4885MEN1 2720/4885
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 KMT2A 2454/4885MAPT 428/4885MEN1 665/4885
US-11760734-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 KMT2A 2454/4885MAPT 428/4885MEN1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.