Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746561 | 0.87 | GLA (0.69) | GLANPSR1ALDH1A1MDM2 | |
| SCHEMBL8958986 | 0.86 | GLA (0.57) | GLANPSR1ALDH1A1MDM2PPARA | |
| SCHEMBL15569868 | 0.83 | NPSR1 (1.00) | GLANPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL16374867 | 0.81 | GLA (0.73) | GLANPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL8247280 | 0.78 | GLA (0.69) | GLANPSR1HDAC6MEN1ALDH1A1 | |
| SCHEMBL9193771 | 0.78 | GLA (0.69) | GLANPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL3363159 | 0.77 | GLA (0.43) | GLANPSR1HDAC8HDAC6HDAC2 | |
| SCHEMBL15647719 | 0.76 | GLA (0.67) | GLANPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL15570301 | 0.76 | GLA (0.67) | GLANPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16460894 | 0.76 | GLA (0.67) | GLANPSR1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393786-B1 | New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical | SCLAVO SPA (IT) | 1996-01-17 | — | — | EP | disclosed |
| EP-0406931-B1 | New analogues of all-bond retroinverted thymopentin, the method for the synthesis of the same and their employment for the preparation of pharmaceutical compositions | SCLAVO SPA (IT) | 1995-03-15 | — | — | EP | disclosed |
| EP-0384523-B1 | New gem-diamino derivatives and their use in the synthesis of retro-inverso peptides | ENIRICERCHE SPA (IT) | 1994-06-01 | — | — | EP | disclosed |
| EP-0375040-B1 | Process for the preparation of retro-inverso peptides and new intermediates thereof | SCLAVO SPA (IT) | 1994-03-16 | — | — | EP | disclosed |
| US-5219988-A | GEM-DIAMINO DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF RETRO-INVERSO PEPTIDES | ENIRICERCHE S.P.A. (IT) | 1993-06-15 | — | — | US | disclosed |
| US-5116947-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND NEW INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1992-05-26 | — | — | US | disclosed |
| US-5061811-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND 1,3-DIOXANE-4,6-DIONE INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1991-10-29 | — | — | US | disclosed |
| EP-0393786-A1 | New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical | SCLAVO S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |
| EP-0384523-A2 | New gem-diamino derivatives and their use in the synthesis of retro-inverso peptides | ENIRICERCHE S.p.A. (IT) | 1990-08-29 | — | — | EP | disclosed |