Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958982 | 0.86 | GLA (0.71) | GLANPSR1MDM2PPARGPPARA | |
| SCHEMBL3097423 | 0.81 | GLA (0.52) | GLANPSR1MAOB | |
| SCHEMBL7417047 | 0.78 | GLA (0.66) | GLANPSR1MDM2 | |
| SCHEMBL16645282 | 0.76 | GLA (0.52) | GLANPSR1MDM2 | |
| SCHEMBL15648921 | 0.76 | GLA (0.52) | GLANPSR1MDM2DAOMAOB | |
| SCHEMBL3088858 | 0.76 | GLA (0.52) | GLANPSR1MDM2DAOMAOB | |
| SCHEMBL16632922 | 0.76 | GLA (0.49) | GLANPSR1DAO | |
| SCHEMBL12746561 | 0.74 | GLA (0.69) | GLANPSR1MDM2DAOALDH1A1 | |
| SCHEMBL6811281 | 0.73 | GLA (0.49) | GLANPSR1MDM2DAOMAOB | |
| SCHEMBL15569868 | 0.73 | NPSR1 (1.00) | GLANPSR1CMA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393786-B1 | New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical | SCLAVO SPA (IT) | 1996-01-17 | — | — | EP | disclosed |
| EP-0406931-B1 | New analogues of all-bond retroinverted thymopentin, the method for the synthesis of the same and their employment for the preparation of pharmaceutical compositions | SCLAVO SPA (IT) | 1995-03-15 | — | — | EP | disclosed |
| EP-0375040-B1 | Process for the preparation of retro-inverso peptides and new intermediates thereof | SCLAVO SPA (IT) | 1994-03-16 | — | — | EP | disclosed |
| US-5116947-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND NEW INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1992-05-26 | — | — | US | disclosed |
| US-5061811-A | PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND 1,3-DIOXANE-4,6-DIONE INTERMEDIATES THEREOF | SCLAVO S.P.A. (IT) | 1991-10-29 | — | — | US | disclosed |
| EP-0393786-A1 | New retro-inverse, one- or more bond bearing analogues of thymopentin, a method for synthesizing the same and their employment for the preparation of pharmaceutical | SCLAVO S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |