SCHEMBL8959083

SCHEMBL8959083

CCCCC=C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.37
DPP7 Q9UHL4 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CCR6 P51684 1/20 0.34
CCR5 P51681 4/20 0.33
KDM4E B2RXH2 1/20 0.30
RAB9A P51151 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28223602 1.00 ABCB1 (0.37) ABCB1DPP7TSHRALDH1A1CCR6
SCHEMBL27148693 1.00 ABCB1 (0.37) ABCB1DPP7TSHRALDH1A1CCR6
SCHEMBL27150036 1.00 ABCB1 (0.37) ABCB1DPP7TSHRALDH1A1CCR6
SCHEMBL27137245 1.00 ABCB1 (0.37) ABCB1DPP7TSHRALDH1A1CCR6
SCHEMBL2130748 0.98 TSHR (0.36) ABCB1DPP7TSHRALDH1A1CCR6
SCHEMBL16760609 0.91 CCR5 (0.40) ABCB1TSHRCCR5
SCHEMBL9062253 0.91 CCR5 (0.40) ABCB1TSHRCCR5
SCHEMBL11229187 0.91 CCR5 (0.40) ABCB1TSHRCCR5
SCHEMBL15467638 0.91 CCR5 (0.40) ABCB1TSHRCCR5
SCHEMBL9801267 0.91 CCR5 (0.40) ABCB1TSHRCCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327421-A1 Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation CU Ventures, Inc. 2024-10-03 US disclosed
EP-3601204-A1 SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION Marquette University (US) 2020-02-05 EP disclosed
US-10144879-B2 Hydrocarbon synthesis methods, apparatus, and systems SARTEC CORPORATION (US) 2018-12-04 US disclosed
WO-2018183800-A1 SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION MARQUETTE UNIVERSITY (US) 2018-10-04 WO disclosed
US-20170029711-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS SARTEC CORPORATION 2017-02-02 US disclosed
US-9388345-B2 Hydrocarbon synthesis methods, apparatus, and systems SARTEC CORPORATION (US) 2016-07-12 US disclosed
US-9382491-B2 Hydrocarbon synthesis methods, apparatus, and systems SARTEC CORPORATION (US) 2016-07-05 US disclosed
US-20140115955-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS SARTEC CORPORATION 2014-05-01 US disclosed
US-20140046104-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS SARTEC CORPORATION 2014-02-13 US disclosed
WO-2014008355-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS MCNEFF CLAYTON V (US) 2014-01-09 WO disclosed
EP-0482834-B1 Process for producing alpha-hydroxyketones TAKASAGO PERFUMERY CO LTD (JP) 1996-01-17 EP disclosed
US-5210315-A Oxidizing olefins using a ruthenium catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-05-11 US disclosed
EP-0482834-A1 Process for producing alpha-hydroxyketones Takasago International Corporation (JP) 1992-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327421-A1 Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation ESR2, GPER1, ESR1 ABCB1 3079/4885DPP7 3780/4885TSHR 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.