SCHEMBL8959111

SCHEMBL8959111

CCCCCCCc1ccc(OCCN)c(Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.74
GLA P06280 1/20 0.74
CSNK2A1 P68400 2/20 0.60
BACE1 P56817 1/20 0.52
HTR2A P28223 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
S1PR2 O95136 1/20 0.48
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
LPAR2 Q9HBW0 1/20 0.48
ATM Q13315 1/20 0.48
APAF1 O14727 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9398654 0.88 SMN1; SMN2 (0.65) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL9398842 0.86 SMN1; SMN2 (0.70) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL9775784 0.84 SMN1; SMN2 (0.60) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10914976 0.82 SMN1; SMN2 (0.54) SMN1; SMN2GLAHTR2AMEN1NPC1
SCHEMBL9399818 0.82 SMN1; SMN2 (0.77) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10981424 0.80 SMN1; SMN2 (0.55) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10975599 0.80 SMN1; SMN2 (0.55) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10979500 0.80 SMN1; SMN2 (0.55) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10975775 0.80 SMN1; SMN2 (0.55) SMN1; SMN2GLACSNK2A1BACE1MEN1
SCHEMBL10982899 0.80 SMN1; SMN2 (0.55) SMN1; SMN2GLACSNK2A1BACE1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed