Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398654 | 0.93 | SMN1; SMN2 (0.65) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL9398842 | 0.91 | SMN1; SMN2 (0.70) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL8959111 | 0.84 | SMN1; SMN2 (0.74) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL9399818 | 0.84 | SMN1; SMN2 (0.77) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10981424 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10975599 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10975775 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10982899 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10986508 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A | |
| SCHEMBL10982363 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |