SCHEMBL8959239

SCHEMBL8959239

CC(C)(C)C1CC(C(C)(C)C)CC(c2ccc(O)cc2)(c2ccc(O)cc2)C1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.45
ESR2 Q92731 7/20 0.45
CYP3A4 P08684 2/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 1/20 0.34
TYR P14679 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GRIN2B Q13224 2/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6451587 0.92 ESR1 (0.47) ESR1ESR2CYP3A4ARHPGD
SCHEMBL9065887 0.90 ESR2 (0.51) ESR1ESR2CYP3A4ARHPGD
SCHEMBL16581452 0.87 ESR2 (0.39) ESR1ESR2CYP3A4
SCHEMBL9065610 0.82 ESR1 (0.40) ESR1ESR2CYP3A4ARHPGD
SCHEMBL9803622 0.80 ESR2 (0.47) ESR1ESR2CYP3A4ARHPGD
SCHEMBL9074756 0.80 ESR1 (0.39) ESR1ESR2CYP3A4ARHPGD
SCHEMBL2042870 0.80 ESR2 (0.52) ESR1ESR2CYP3A4ARHPGD
SCHEMBL2498416 0.78 ESR2 (0.53) ESR1ESR2CYP3A4ARHPGD
SCHEMBL23250802 0.75 ESR2 (0.46) ESR1ESR2CYP3A4ARHPGD
SCHEMBL9066136 0.75 ESR1 (0.40) ESR1ESR2CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0481287-B1 Method for the production of substituted cyclohexylidenebisphenols BAYER AG (DE) 1996-01-17 EP disclosed
EP-0374623-B1 POLYCARBONATES FROM POLYSUBSTITUTED CYCLOHEXYLIDENE DIPHENOLS BAYER AG (DE) 1992-05-27 EP disclosed
EP-0481287-A2 Method for the production of substituted cyclohexylidenebisphenols BAYER AG (DE) 1992-04-22 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
US-5034457-A Polycarbonate for use in molding materials for laminated films and for electronics BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-5021542-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
EP-0387593-A2 Thermoplastic alloys of polycarbonates based on substituted cyclohexylidenbisphenols BAYER AG (DE) 1990-09-19 EP disclosed
EP-0374623-A2 Polycarbonates from polysubstituted cyclohexylidene diphenols BAYER AG (DE) 1990-06-27 EP disclosed