Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074756 | 0.83 | ESR1 (0.39) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL9066161 | 0.82 | ESR2 (0.45) | ESR1ESR2SHBGCYP3A4AR | |
| SCHEMBL8959239 | 0.82 | ESR1 (0.45) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL9064719 | 0.81 | ESR2 (0.46) | ESR1ESR2SHBG | |
| SCHEMBL6451587 | 0.78 | ESR1 (0.47) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL6449291 | 0.75 | ESR2 (0.48) | ESR1ESR2SHBGCYP3A4AR | |
| SCHEMBL9803622 | 0.74 | ESR2 (0.47) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL9065887 | 0.73 | ESR2 (0.51) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL16581452 | 0.71 | ESR2 (0.39) | ESR1ESR2CYP3A4 | |
| SCHEMBL23250802 | 0.69 | ESR2 (0.46) | ESR1ESR2CYP3A4ARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5010163-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0374630-A2 | Polycarbonates from cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |