SCHEMBL8959266

SCHEMBL8959266

CCCCCCCC[N+](CCCCCCCC)(CCCCCCCC)Cc1ccc(C)cc1.CCCCCCCC[N+](CCCCCCCC)(CCCCCCCC)Cc1ccc(C)cc1.O=S(=O)([O-])c1cccc2c(S(=O)(=O)[O-])cccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.50
HTT P42858 3/20 0.50
TSHR P16473 2/20 0.50
CYP2C19 P33261 2/20 0.50
LMNA P02545 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2C9 P11712 1/20 0.50
HIF1A Q16665 1/20 0.50
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DNM1 Q05193 2/20 0.37
MAPK1 P28482 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCHR1 Q99705 1/20 0.36
PSMD14 O00487 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959248 0.95 KCNH2 (0.44) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL8959272 0.88 HTT (0.42) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL8959251 0.82 TTR (0.40) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL10966371 0.81 HTT (0.59) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL16412126 0.80 DNM1 (0.43) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL10966370 0.80 DNM1 (0.48) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL10966935 0.80 HTT (0.58) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL10966933 0.79 DNM1 (0.47) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL8959259 0.79 DNM1 (0.46) KCNH2HTTTSHRCYP2C19LMNA
SCHEMBL8959209 0.78 KCNH2 (0.43) KCNH2HTTTSHRCYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545502-A CONTAINING SPECIFIED QUATERNARY AMMONIUM SALT AS CHARGE CONTROL AGENT MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-13 US disclosed
EP-0602566-B1 Electrostatic image-developing toner MITSUBISHI CHEM CORP (JP) 1996-07-31 EP disclosed
EP-0602566-A1 Electrostatic image-developing toner Mitsubishi Chemical Corporation (JP) 1994-06-22 EP disclosed