SCHEMBL8959322

SCHEMBL8959322

ON=C1CCCC(c2c[c]ccc2)C1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.44
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1570533 0.82 ESR2 (0.54) ESR2
SCHEMBL1570534 0.82 ESR2 (0.54) ESR2
SCHEMBL593071 0.74 CYP11B2 (0.39) ESR2
SCHEMBL23110 0.74 CYP11B2 (0.44) TSHR
SCHEMBL14620989 0.73 ESR2 (0.55) ESR2TSHRCASP1
SCHEMBL23071376 0.73 CYP11B2 (0.47) TSHR
SCHEMBL21454 0.73 CYP11B2 (0.47) TSHR
SCHEMBL677487 0.73 CYP11B2 (0.47) TSHR
SCHEMBL15541691 0.72 ESR2 (0.55) ESR2TSHR
SCHEMBL15541693 0.72 ESR2 (0.55) ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692249-A1 Compounds bearing one or more oxime functions, stabilized in aqueous solution, process to prepare them, and their use as drugs LABORATOIRES JACQUES LOGEAIS Société dite: (FR) 1996-01-17 EP disclosed