Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344083 | 0.84 | KCNH2 (0.46) | SIGMAR1KCNH2OPRM1DRD3 | |
| SCHEMBL1343597 | 0.80 | ACP3 (0.44) | SIGMAR1KCNH2 | |
| SCHEMBL12500369 | 0.77 | SIGMAR1 (0.66) | SIGMAR1KCNH2DRD2DRD4OPRM1 | |
| SCHEMBL17996055 | 0.77 | ACP3 (0.42) | SIGMAR1KCNH2 | |
| SCHEMBL12500566 | 0.76 | SIGMAR1 (0.67) | SIGMAR1KCNH2DRD2DRD4OPRM1 | |
| SCHEMBL10453660 | 0.74 | SIGMAR1 (0.91) | SIGMAR1KCNH2DRD3 | |
| SCHEMBL9768701 | 0.74 | SIGMAR1 (0.86) | SIGMAR1KCNH2 | |
| SCHEMBL9364530 | 0.74 | CCR1 (0.48) | SIGMAR1 | |
| SCHEMBL11932501 | 0.74 | SIGMAR1 (0.66) | SIGMAR1KCNH2 | |
| SCHEMBL10451727 | 0.73 | CCR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496818-A | OIL-IN-WATER TYPE; DISPERSED LIPID PHASE OF VEGETABLE OIL, PHOSPHOLIPID EMULSIFIER AND STRONGLY BASIC HYDROPHOBIC PHARMACEUTICAL; AQUEOUS PHASE WITH BUFFER AND SMALL AMOUNT OF IONIZED PHARMACEUTICAL; POSITIVE CHARGE AT EMULSION INTERFACE | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | claimed |
| EP-0456106-B1 | Stable emulsion for pharmaceutical administration, process for its preparation and use thereof as pharmaceutical | KNOLL AG (DE) | 1994-12-07 | — | — | EP | claimed |
| EP-0456106-A2 | Stable emulsion for pharmaceutical administration, process for its preparation and use thereof as pharmaceutical | KNOLL AG (DE) | 1991-11-13 | — | — | EP | claimed |
| US-5496818-A | OIL-IN-WATER TYPE; DISPERSED LIPID PHASE OF VEGETABLE OIL, PHOSPHOLIPID EMULSIFIER AND STRONGLY BASIC HYDROPHOBIC PHARMACEUTICAL; AQUEOUS PHASE WITH BUFFER AND SMALL AMOUNT OF IONIZED PHARMACEUTICAL; POSITIVE CHARGE AT EMULSION INTERFACE | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0456106-B1 | Stable emulsion for pharmaceutical administration, process for its preparation and use thereof as pharmaceutical | KNOLL AG (DE) | 1994-12-07 | — | — | EP | disclosed |
| EP-0456106-A2 | Stable emulsion for pharmaceutical administration, process for its preparation and use thereof as pharmaceutical | KNOLL AG (DE) | 1991-11-13 | — | — | EP | disclosed |