Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359512 | 0.90 | ITGB3 (0.41) | EDNRBEDNRAITGB3ITGA2BHTR2A | |
| SCHEMBL7425624 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BF2 | |
| SCHEMBL7361166 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7361582 | 0.76 | EDNRB (0.34) | EDNRBEDNRATRPA1 | |
| SCHEMBL7363490 | 0.74 | ITGB3 (0.37) | EDNRBEDNRAITGB3ITGA2BHTR2A | |
| SCHEMBL7358573 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7362403 | 0.74 | CHRM5 (0.38) | EDNRBEDNRAHTR2A | |
| SCHEMBL7357511 | 0.73 | ITGB3 (0.47) | ITGB3ITGA2BTRPA1F2 | |
| SCHEMBL7363456 | 0.73 | ITGB3 (0.52) | ITGB3ITGA2BTRPA1F2 | |
| SCHEMBL7356103 | 0.72 | ITGB3 (0.57) | ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |