Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959983 | 0.91 | SRD5A1 (0.53) | SRD5A1SRD5A2CDC25AICMTMCL1 | |
| SCHEMBL8959655 | 0.88 | SRD5A1 (0.49) | SRD5A1SRD5A2CNR1CREBBP | |
| SCHEMBL8959830 | 0.88 | CNR1 (0.49) | SRD5A1SRD5A2CNR1CREBBP | |
| SCHEMBL8959708 | 0.86 | CNR1 (0.51) | SRD5A1SRD5A2CNR1CREBBPCDC25A | |
| SCHEMBL9288243 | 0.83 | OXER1 (0.38) | SRD5A1SRD5A2PTGS2MCL1OXER1 | |
| SCHEMBL9337367 | 0.79 | SRD5A1 (0.66) | SRD5A1SRD5A2CNR1CREBBP | |
| SCHEMBL8959973 | 0.79 | SRD5A1 (0.59) | SRD5A1SRD5A2CNR1 | |
| SCHEMBL8960038 | 0.79 | CNR1 (0.56) | CNR1CREBBPCDC25AICMTMCL1 | |
| SCHEMBL8959858 | 0.79 | SRD5A1 (0.58) | SRD5A1SRD5A2CNR1CREBBP | |
| SCHEMBL9334109 | 0.78 | SRD5A1 (0.65) | SRD5A1SRD5A2CNR1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |