Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074411 | 1.00 | LMNA (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL27801117 | 1.00 | LMNA (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL31528891 | 1.00 | LMNA (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL30881605 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL18723113 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL21118320 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL9234237 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL18723162 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL6420270 | 0.97 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL6446817 | 0.97 | SMN1; SMN2 (0.58) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |