Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 1.00 |
| ▸ | HTR2A | P28223 | 14/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234276 | 1.00 | HTR2C (1.00) | HTR2CHTR2APRMT5P2RX7 | |
| SCHEMBL8959931 | 1.00 | HTR2C (1.00) | HTR2CHTR2APRMT5P2RX7 | |
| Fumaric Acid SCHEMBL8959716 | 0.88 | HTR2C (0.77) | HTR2CHTR2APRMT5P2RX7 | |
| Fumaric Acid SCHEMBL8959706 | 0.88 | HTR2C (0.77) | HTR2CHTR2APRMT5P2RX7 | |
| SCHEMBL8959689 | 0.83 | HTR2C (0.71) | HTR2CHTR2APRMT5P2RX7 | |
| SCHEMBL8959700 | 0.83 | HTR2C (0.71) | HTR2CHTR2APRMT5P2RX7 | |
| SCHEMBL27343269 | 0.78 | HTR2C (0.64) | HTR2CHTR2APRMT5 | |
| SCHEMBL2120779 | 0.77 | HTR2C (0.62) | HTR2CHTR2APRMT5P2RX7 | |
| SCHEMBL14527150 | 0.74 | HTR2C (0.61) | HTR2CHTR2A | |
| SCHEMBL24656041 | 0.74 | HTR2C (0.58) | HTR2CHTR2APRMT5P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |