Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720868 | 0.85 | LMNA (0.71) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL6839377 | 0.85 | KDM4E (0.57) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL11595431 | 0.81 | KDM4E (0.55) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL27371740 | 0.80 | KDM4E (0.55) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL8070827 | 0.79 | HTT (0.51) | LMNAKDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL8070825 | 0.79 | HTT (0.51) | LMNAKDM4EPOLBMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7337871 | 0.79 | KDM4E (0.54) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL7331745 | 0.78 | LMNA (0.47) | LMNAKDM4EPOLBMAPTACHE | |
| SCHEMBL11592796 | 0.78 | LMNA (0.40) | LMNAKDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL21798820 | 0.77 | HTT (0.57) | LMNAKDM4EPOLBMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | claimed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | claimed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | claimed |
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | disclosed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | disclosed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |
| US-4104402-A | BRONCHODILATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-08-01 | — | — | US | disclosed |
| US-4010202-A | TREATMENT OF ASTHMA AND ARRHYTHMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-01 | — | — | US | disclosed |