SCHEMBL8960374

SCHEMBL8960374

COCCOc1nnnc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2085970 0.82 CSNK2A1 (0.32)
SCHEMBL10886942 0.78 PLAU (0.32) TSHR
SCHEMBL2370879 0.74 CYP1A2 (0.41)
SCHEMBL9514560 0.72 PLAU (0.31) TSHR
SCHEMBL9169736 0.69 TDP1 (0.37) TSHR
SCHEMBL11145827 0.68 TSHR (0.41) TSHRTLR8TLR7
SCHEMBL11815177 0.67 SMN1; SMN2 (0.39) TSHR
SCHEMBL11106621 0.65
SCHEMBL10624575 0.63
SCHEMBL142354 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693536-A1 Azo dyes with a chlorotriazine group BAYER AG (DE) 1996-01-24 EP disclosed