Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332621 | 0.84 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL217810 | 0.84 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL10990116 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL5586518 | 0.83 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL28874774 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL8523738 | 0.81 | — | — | |
| SCHEMBL25178832 | 0.81 | TSHR (0.54) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL25185278 | 0.81 | TSHR (0.54) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL9718874 | 0.81 | TSHR (0.54) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL25178019 | 0.81 | TSHR (0.54) | TSHRALDH1A1TDP1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693284-A1 | PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT | TEIJIN LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |