Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130119 | 0.89 | APP (0.72) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL18429723 | 0.86 | APP (1.00) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL28073298 | 0.86 | APP (0.69) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL11078412 | 0.86 | APP (0.69) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL11083926 | 0.83 | APP (0.65) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL9737624 | 0.82 | APP (0.63) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL10854605 | 0.80 | APP (0.60) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL22567940 | 0.79 | APP (0.59) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL6724287 | 0.78 | APP (0.58) | APPGAAMAPTLMNAJAK2 | |
| SCHEMBL6356278 | 0.78 | MAPT (0.60) | APPGAAMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486899-B1 | Polyimide resin and preparation thereof | GRACE W R & CO (US) | 1996-01-24 | — | — | EP | claimed |
| US-5200449-A | Solvent concentrates consisting of phenol/4-methoxy phenol or phenol/2,6-dimethyl phenol; storage stability, halogen-free solvent, nontoxic | W. R. GRACE & CO.-CONN. (US) | 1993-04-06 | — | — | US | claimed |
| EP-0486899-A1 | Polyimide resin and preparation thereof | W.R. Grace & Co.-Conn. (US) | 1992-05-27 | — | — | EP | claimed |
| EP-0486899-B1 | Polyimide resin and preparation thereof | GRACE W R & CO (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5200449-A | Solvent concentrates consisting of phenol/4-methoxy phenol or phenol/2,6-dimethyl phenol; storage stability, halogen-free solvent, nontoxic | W. R. GRACE & CO.-CONN. (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0486899-A1 | Polyimide resin and preparation thereof | W.R. Grace & Co.-Conn. (US) | 1992-05-27 | — | — | EP | disclosed |