Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030039 | 0.83 | ALDH1A1 (0.60) | APPALDH1A1CYP3A4ALOX5AR | |
| SCHEMBL8960607 | 0.82 | APP (0.76) | APPALDH1A1PTGS1MAPTGAA | |
| SCHEMBL130119 | 0.80 | APP (0.72) | APPALDH1A1PTGS1MAPTGAA | |
| SCHEMBL10689679 | 0.80 | HTR1A (0.48) | APPALDH1A1PTGS1MAPTGAA | |
| SCHEMBL18429723 | 0.77 | APP (1.00) | APPMAPTGAAJAK2LMNA | |
| SCHEMBL28073298 | 0.77 | APP (0.69) | APPMAPTGAAJAK2LMNA | |
| SCHEMBL11078412 | 0.77 | APP (0.69) | APPALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL9625666 | 0.77 | HTR1A (0.56) | ALDH1A1MAPTLMNAKDM4EHTR1A | |
| SCHEMBL9094178 | 0.77 | ALDH1A1 (0.57) | APPALDH1A1CYP3A4ALOX5AR | |
| SCHEMBL9736605 | 0.76 | KMT2A (0.56) | ALDH1A1CYP3A4ALOX5ARPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149462-A | Used as ferroelectric liquid crystal | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0409066-A2 | Optically active compound for liquid crystal and its use | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |