SCHEMBL8960736

SCHEMBL8960736

Cc1c(N)ccc(N)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
CYP3A4 P08684 11/20 0.48
TSHR P16473 8/20 0.48
PIK3CA P42336 1/20 0.48
TDP1 Q9NUW8 5/20 0.41
THRB P10828 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
MCL1 Q07820 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX15 P16050 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767710 0.83 CYP3A4 (0.46) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL6403160 0.83 CYP3A4 (0.46) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL3871698 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL5518280 0.83 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL2906897 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL8282372 0.83 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL767268 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4TSHRPIK3CATDP1
Hydrochloric Acid SCHEMBL21879618 0.81 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL24717442 0.79 ALDH1A1 (0.38) ALDH1A1CYP3A4TSHRPIK3CATDP1
SCHEMBL6562515 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4TSHRPIK3CATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510429-A Compound containing methyl isoxazole structure, and preparation method and application thereof 中国农业大学 2024-02-06 CN disclosed
EP-1891038-B1 SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS LILLY CO ELI (US) 2008-10-29 EP disclosed
EP-0240371-B2 Method of processing lightsensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1996-01-31 EP disclosed
US-5082765-A Developers containing aromatic primary amines in combination w ith sensitizers KONICA CORPORATION (JP) 1992-01-21 US disclosed
EP-0240371-A2 Method of processing lightsensitive silver halide photographic material KONICA CORPORATION (JP) 1987-10-07 EP disclosed
US-4551422-A COLOR FILMS; PHENOLIC COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-05 US disclosed
EP-0116428-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1984-08-22 EP disclosed