Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960845 | 0.96 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2USP2ALDH1A1 | |
| SCHEMBL8961110 | 0.88 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2USP2ALDH1A1 | |
| SCHEMBL6076229 | 0.87 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2USP2ALDH1A1 | |
| SCHEMBL6075426 | 0.86 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2USP2ALDH1A1 | |
| SCHEMBL8961143 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2ALDH1A1BCHE | |
| SCHEMBL8070297 | 0.85 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2USP2ALDH1A1 | |
| SCHEMBL8961010 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2ALDH1A1BCHE | |
| SCHEMBL8961103 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2ALDH1A1BCHE | |
| SCHEMBL8961119 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961109 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |