SCHEMBL8960895

SCHEMBL8960895

O=C(c1ccccc1)c1ccc(Oc2cccc(Oc3ccc(C(=O)c4ccccc4)cc3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.59
F2 P00734 3/20 0.59
F10 P00742 3/20 0.59
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
ST14 Q9Y5Y6 1/20 0.59
ELANE P08246 3/20 0.55
POLB P06746 1/20 0.54
HSD17B14 Q9BPX1 1/20 0.52
ALDH1A1 P00352 1/20 0.52
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
STS P08842 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206981 0.85 F2 (0.46) SRD5A2F2F10PRSS1PRSS2
SCHEMBL10615184 0.85 F2 (0.62) SRD5A2F2F10PRSS1PRSS2
SCHEMBL9491441 0.84 L3MBTL1 (0.57) SRD5A2F2F10PRSS1PRSS2
SCHEMBL28938440 0.84 SRD5A2 (0.80) SRD5A2ELANEPOLBALDH1A1STS
SCHEMBL124917 0.84 SRD5A2 (0.80) SRD5A2ELANEPOLBALDH1A1STS
SCHEMBL9809047 0.84 SRD5A2 (0.80) SRD5A2ELANEPOLBALDH1A1STS
SCHEMBL9419497 0.84 SRD5A2 (0.80) SRD5A2ELANEPOLBALDH1A1STS
SCHEMBL10962603 0.83 ELANE (0.46) SRD5A2F2F10PRSS1PRSS2
SCHEMBL7708809 0.83 SRD5A2 (0.61) SRD5A2ELANEPOLBALDH1A1STS
SCHEMBL1069817 0.82 SRD5A2 (0.84) SRD5A2ELANEPOLBALDH1A1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451556-B1 Stabilised polyaryletherketone - moulding compounds BASF AG (DE) 1996-01-10 EP claimed
US-5334642-A Includes organic compound which has a base constant within the range 2 to 12 and boiling point higher than 300 degrees BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
EP-0451556-B1 Stabilised polyaryletherketone - moulding compounds BASF AG (DE) 1996-01-10 EP disclosed
US-5334642-A Includes organic compound which has a base constant within the range 2 to 12 and boiling point higher than 300 degrees BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed