Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960874 | 0.96 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8961100 | 0.89 | MTNR1A (0.70) | MTNR1AMTNR1BEPHX1NPC1RAB9A | |
| SCHEMBL8961144 | 0.87 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8960806 | 0.86 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961073 | 0.86 | MTNR1A (0.74) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8961161 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1BEPHX1NPC1TP53 | |
| SCHEMBL8961221 | 0.85 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8961004 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961088 | 0.84 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8960969 | 0.84 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |