SCHEMBL8960923

SCHEMBL8960923

CCCOc1ccc2cc(C(=O)c3ccccc3)cc(CCNC(C)=O)c2c1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 0.77
MTNR1B P49286 14/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961135 0.94 MTNR1A (0.74) MTNR1AMTNR1B
SCHEMBL8960904 0.92 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL8961107 0.88 MTNR1A (0.64) MTNR1AMTNR1B
SCHEMBL8961249 0.88 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL8526049 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8960965 0.86 MTNR1A (0.74) MTNR1AMTNR1B
SCHEMBL8961140 0.86 MTNR1A (0.74) MTNR1AMTNR1B
SCHEMBL6246660 0.85 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL8961094 0.85 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL8961104 0.84 MTNR1A (0.77) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552418-A FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM ADIR ET COMPAGNIE (FR) 1996-09-03 US disclosed