Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.73 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961140 | 0.89 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8960953 | 0.88 | MTNR1A (0.72) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8960920 | 0.86 | MTNR1A (0.71) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8961226 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7831321 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8961107 | 0.84 | MTNR1A (0.64) | MTNR1AMTNR1B | |
| SCHEMBL6248768 | 0.84 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8961028 | 0.83 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8961081 | 0.83 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL8960681 | 0.82 | MTNR1A (0.63) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |