Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.79 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960991 | 0.95 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2KDM4EHSD17B10 | |
| SCHEMBL8961176 | 0.94 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2KDM4EHSD17B10 | |
| SCHEMBL8961115 | 0.93 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8960969 | 0.90 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8526049 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961129 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8960891 | 0.87 | MTNR1A (0.70) | MTNR1AMTNR1BKDM4ETSHRHSD17B10 | |
| SCHEMBL8961126 | 0.86 | MTNR1A (0.84) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961221 | 0.86 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961127 | 0.86 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |