Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 9/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785167 | 0.84 | HSD17B3 (0.63) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL18986303 | 0.84 | HSD17B3 (0.63) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL12211390 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ECA12CA9GAA | |
| SCHEMBL205724 | 0.79 | KDM4E (0.46) | AKR1B1ALDH1A1KDM4ECA12GAA | |
| SCHEMBL27075158 | 0.79 | AKR1B1 (0.53) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL16197957 | 0.79 | HSD17B3 (0.52) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL17179700 | 0.78 | ALDH1A1 (0.62) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL23499580 | 0.78 | AKR1B1 (0.52) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL28328438 | 0.78 | HSD17B3 (0.63) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 | |
| SCHEMBL15654047 | 0.77 | KDM4E (0.49) | HSD17B3AKR1B1ALDH1A1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413152-B1 | 7-Hydroxy coumarins having substitutions in the 4 position | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5247099-A | Process for synthesis of 7-hydroxy coumarins having substitutions in the 4-position | ABBOTT LABORATORIES (US) | 1993-09-21 | — | — | US | disclosed |
| US-5208350-A | Fluorescent dyes | ABBOTT LABORATORIES (US) | 1993-05-04 | — | — | US | disclosed |