Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.70 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961037 | 0.95 | MTNR1A (0.74) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961161 | 0.89 | MTNR1A (0.69) | MTNR1AHTR2CMTNR1BMEN1EPHX1 | |
| SCHEMBL8961100 | 0.88 | MTNR1A (0.70) | MTNR1AHTR2CMTNR1BMEN1EPHX1 | |
| SCHEMBL6076328 | 0.87 | MTNR1A (0.52) | MTNR1AHTR2CMTNR1BMEN1EPHX1 | |
| SCHEMBL6077072 | 0.86 | EPHX1 (0.58) | MTNR1AMEN1EPHX1KMT2ANPC1 | |
| SCHEMBL8961302 | 0.86 | MTNR1A (0.90) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961074 | 0.85 | MTNR1A (0.92) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961082 | 0.83 | MTNR1A (0.71) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8960796 | 0.83 | MTNR1A (0.71) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961090 | 0.83 | MTNR1A (0.71) | MTNR1AHTR2CMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |