Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961022 | 0.89 | MTNR1A (0.54) | MTNR1AHTR2CMTNR1BHTR2B | |
| SCHEMBL8961093 | 0.89 | MTNR1A (0.68) | MTNR1AHTR2CMTNR1BHTR2B | |
| SCHEMBL8961241 | 0.83 | MTNR1A (0.68) | MTNR1AHTR2CMTNR1BHTR2B | |
| SCHEMBL6258031 | 0.80 | MTNR1A (0.84) | MTNR1AHTR2CMTNR1BHTR2B | |
| SCHEMBL8961160 | 0.79 | MTNR1A (0.73) | MTNR1AHTR2CMTNR1BHTR2B | |
| SCHEMBL8961121 | 0.79 | MTNR1A (0.71) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8960824 | 0.77 | MTNR1A (0.69) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961218 | 0.76 | MTNR1A (0.68) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961098 | 0.76 | MTNR1A (0.72) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8960946 | 0.75 | HTR2C (0.67) | MTNR1AHTR2CMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |