SCHEMBL8961201

SCHEMBL8961201

O=C(Oc1ccc(CO)cc1)c1ccc(C(=O)Oc2ccc(CO)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.53
PRSS1 P07477 5/20 0.53
F2 P00734 4/20 0.53
PRSS2 P07478 4/20 0.53
PRSS3 P35030 4/20 0.53
PARP10 Q53GL7 1/20 0.52
TMPRSS2 O15393 1/20 0.50
KLK1 P06870 1/20 0.50
KMT2A Q03164 5/20 0.46
HGFAC Q04756 1/20 0.46
MEN1 O00255 1/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TP53 P04637 1/20 0.46
LTA4H P09960 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646241 1.00 HSD17B10 (0.53) HSD17B10PRSS1F2PRSS2PRSS3
SCHEMBL14139256 0.93 RXRA (0.50) HSD17B10PRSS1F2PRSS2PRSS3
SCHEMBL21389668 0.93 MEN1 (0.55) HSD17B10PRSS1F2PRSS2PRSS3
SCHEMBL12536656 0.91 PRSS1 (0.56) PRSS1F2PRSS2PRSS3PARP10
SCHEMBL5582569 0.91 SMN1; SMN2 (0.60) PRSS1KMT2ALMNACYP1A2CYP2C9
SCHEMBL23783490 0.91 ELANE (0.51) HSD17B10PRSS1F2PRSS2PRSS3
SCHEMBL18020586 0.91 PRSS1 (0.56) PRSS1F2PRSS2PRSS3PARP10
SCHEMBL22688039 0.91 PRSS1 (0.66) HSD17B10PRSS1F2PRSS2PRSS3
SCHEMBL12536667 0.91 SMN1; SMN2 (0.60) PRSS1KMT2ALMNACYP1A2CYP2C9
SCHEMBL1546405 0.90 PARP10 (0.61) HSD17B10PARP10KMT2AMEN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3747301-A1 FOOTWEAR AND OTHER ARTICLES FORMED BY JET EXTRUSION PROCESSES The North Face Apparel Corp. (US) 2020-12-09 EP disclosed
US-10793983-B2 Footwear and other articles formed by jet extrusion processes THE NORTH FACE APPAREL CORP. (US) 2020-10-06 US disclosed
US-20170306539-A1 FOOTWEAR AND OTHER ARTICLES FORMED BY JET EXTRUSION PROCESSES THE NORTH FACE APPAREL CORP. (US) 2017-10-26 US disclosed
US-5508069-A COMPRISING ORIENTATION THERMOTROPIC AROMATIC POLYESTER FILMS SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1996-04-16 US disclosed
US-5108863-A Processes for the preparation of encapsulated toner compositions XEROX CORPORATION (US) 1992-04-28 US disclosed
US-4954412-A Processes for the preparation of encapsulated toner compositions XEROX CORPORATION (US) 1990-09-04 US disclosed