Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589999 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9591311 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9349567 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9345318 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9346319 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9590846 | 0.90 | TDP1 (0.43) | TDP1GPR119ITGB3ITGA2B | |
| SCHEMBL9188856 | 0.88 | TDP1 (0.44) | TDP1HTR1AHTR1DHTR1BGPR119 | |
| SCHEMBL9188863 | 0.88 | TDP1 (0.44) | TDP1HTR1AHTR1DHTR1BGPR119 | |
| SCHEMBL9592319 | 0.86 | GPR119 (0.45) | TDP1GPR119HRH3 | |
| SCHEMBL9348727 | 0.86 | GPR119 (0.45) | TDP1HTR1AHTR1DHTR1BGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398155-B1 | Cyclopropylalkyl or cycloalkenyl compounds, process for their preparation and their use in liquid crystal mixtures | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0398155-A2 | Cyclopropylalkyl or cycloalkenyl compounds, process for their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-22 | — | — | EP | disclosed |