Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.77 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609009 | 0.87 | MTNR1A (1.00) | MTNR1AHTR2CMTNR1BALDH1A1 | |
| SCHEMBL8960879 | 0.85 | MTNR1A (0.67) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961260 | 0.85 | MTNR1A (0.81) | MTNR1AHTR2CMTNR1BALDH1A1 | |
| SCHEMBL8961074 | 0.83 | MTNR1A (0.92) | MTNR1AHTR2CMTNR1BALDH1A1 | |
| SCHEMBL8961122 | 0.83 | MTNR1A (0.92) | MTNR1AHTR2CMTNR1BALDH1A1 | |
| SCHEMBL8961302 | 0.82 | MTNR1A (0.90) | MTNR1AHTR2CMTNR1BALDH1A1 | |
| SCHEMBL8961193 | 0.82 | MTNR1A (0.76) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961037 | 0.81 | MTNR1A (0.74) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL6258031 | 0.81 | MTNR1A (0.84) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961082 | 0.79 | MTNR1A (0.71) | MTNR1AHTR2CMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |