Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961218 | 0.88 | MTNR1A (0.68) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961085 | 0.87 | MTNR1A (0.80) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961125 | 0.87 | MTNR1A (0.80) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8070336 | 0.86 | MTNR1A (0.72) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961104 | 0.85 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL8960681 | 0.85 | MTNR1A (0.63) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8610088 | 0.85 | MTNR1A (1.00) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961094 | 0.85 | MTNR1A (0.73) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961271 | 0.84 | MTNR1A (0.72) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8961038 | 0.83 | MTNR1A (0.74) | MTNR1AHTR2CMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |