Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16045520 | 0.82 | TSHR (0.46) | TSHRADRA1APDE4DGAASMN1; SMN2 | |
| SCHEMBL8961136 | 0.78 | LMNA (0.41) | TSHRSMN1; SMN2LMNA | |
| SCHEMBL7638571 | 0.78 | TET2 (0.38) | TSHR | |
| SCHEMBL11451567 | 0.76 | TSHR (0.40) | TSHRADRA1APDE4DGAASMN1; SMN2 | |
| SCHEMBL7641932 | 0.72 | TSHR (0.42) | TSHRADRA1APDE4DGAASMN1; SMN2 | |
| SCHEMBL141672 | 0.72 | GAA (0.41) | TSHRGAASMN1; SMN2LMNA | |
| SCHEMBL16046615 | 0.72 | TSHR (0.46) | TSHRADRA1APDE4DGAASMN1; SMN2 | |
| SCHEMBL7640057 | 0.71 | TSHR (0.36) | TSHRADRA1APDE4DGAASMN1; SMN2 | |
| SCHEMBL7634041 | 0.71 | TSHR (0.36) | TSHRADRA1APDE4DLMNA | |
| SCHEMBL7637945 | 0.70 | TSHR (0.43) | TSHRADRA1APDE4DGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693473-A1 | Method of producing pivaloylacetic acid ester | UBE INDUSTRIES, LTD. (JP) | 1996-01-24 | — | — | EP | disclosed |