Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.69 |
| ▸ | PREP | P48147 | 2/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 5/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920319 | 1.00 | ELANE (0.69) | ELANEPREPRENCMA1CTRB1 | |
| SCHEMBL8611274 | 1.00 | ELANE (0.69) | ELANEPREPRENCMA1CTRB1 | |
| SCHEMBL10081594 | 0.91 | ELANE (0.64) | ELANEPREPCMA1 | |
| SCHEMBL8611215 | 0.88 | PREP (0.67) | ELANEPREPRENCYP1A2ACE | |
| SCHEMBL8611219 | 0.88 | PREP (0.67) | ELANEPREPRENCYP1A2ACE | |
| SCHEMBL11517511 | 0.88 | PREP (0.70) | ELANEPREPRENCMA1CTRB1 | |
| SCHEMBL7392861 | 0.87 | PREP (0.59) | ELANEPREPRENCMA1CTRB1 | |
| SCHEMBL8922399 | 0.85 | ELANE (0.51) | ELANEPREPCMA1 | |
| SCHEMBL8921637 | 0.85 | ELANE (0.51) | ELANEPREPCMA1 | |
| SCHEMBL7392499 | 0.85 | PREP (0.57) | ELANEPREPRENCMA1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693080-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022898-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |