Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.67 |
| ▸ | ELANE | P08246 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611219 | 1.00 | PREP (0.67) | PREPELANEACELMNAREN | |
| SCHEMBL22209468 | 0.96 | PREP (0.72) | PREPELANEACELMNAACE2 | |
| SCHEMBL7334484 | 0.96 | PREP (0.72) | PREPELANEACELMNAACE2 | |
| SCHEMBL7871516 | 0.96 | PREP (0.72) | PREPELANEACELMNAACE2 | |
| SCHEMBL10657907 | 0.92 | PREP (0.67) | PREPELANEACELMNAACE2 | |
| SCHEMBL9438697 | 0.92 | PREP (0.67) | PREPELANEACELMNAACE2 | |
| SCHEMBL9438980 | 0.92 | PREP (0.67) | PREPELANEACELMNAACE2 | |
| SCHEMBL9438701 | 0.92 | PREP (0.67) | PREPELANEACELMNAACE2 | |
| SCHEMBL16000756 | 0.89 | PREP (0.71) | PREPELANEACELMNAREN | |
| SCHEMBL8611274 | 0.88 | ELANE (0.69) | PREPELANEACERENCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693080-B1 | NEW GLUCOCORTICOIDS | SCHERING AG (DE) | 1998-04-22 | — | — | EP | disclosed |
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0693080-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022898-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |
| US-4554100-A | ENZYME INHIBITORS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1985-11-19 | — | — | US | disclosed |